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Surname : BECQUART
Name : Pierre
Team : SEE
Grade : CR1
Email address : This email address is being protected from spambots. You need JavaScript enabled to view it.
Telephone : (+33) 4 67 41 63 32
Fax : (+33) 4 67 41 62 99
Office : 164
Locality : IRD Montpellier
Employer : IRD

Publications :

Groc S, Abbate JL, Le Gal F, Gerber A, Tuaillon E, Albert JL, Nkoghe D, Leroy EM, Roche B, Becquart P (2019) High prevalence and diversity of hepatitis B and hepatitis delta virus in Gabon. Journal of Viral Hepatitis 26: 170-182 doi

Makiala-Mandanda S, Ahuka-Mundeke S, Abbate JL, Pukuta-Simbu E, Nsio-Mbeta J, Berthet N, Leroy EM, Becquart P, Muyembe-Tamfum JJ (2018) Identification of dengue and chikungunya cases among suspected cases of yellow fever in the Democratic Republic of the Congo. Vector-Borne and Zoonotic Diseases 18: 364-370 doi

Brazier L, Elguero E, Koumavor CK, Renaud N, Prugnolle F, Thomas F, Ategbo S, Engoba M, Obengui, Leroy EM, Durand P, Renaud F, Becquart P (2017) Evolution in fecal bacterial/viral composition in infants of two central African countries (Gabon and Republic of the Congo) during their first month of life. PLoS One 12: e0185569 doi

Makiala-Mandanda S, Le Gal F, Ngwaka-Matsung N, Ahuka-Mundeke S, Onanga R, Bivigou-Mboumba B, Pukuta-Simbu E, Gerber A, Abbate JL, Mwamba D, Berthet N, Leroy EM, Muyembe-Tamfum JJ, Becquart P (2017) High prevalence and diversity of hepatitis viruses in suspected cases of yellow fever in the Democratic Republic of Congo. Journal of Clinical Microbiology 55: 1299-1312 doi

Elguero E, Delicat-Loembet LM, Rougeron V, Arnathau C, Roche B, Becquart P, Gonzalez JP, Nkoghe D, Sica L, Leroy EM, Durand P, Ayala FJ, Ollomo B, Renaud F, Prugnolle F (2015) Malaria continues to select for sickle cell trait in central africa. Proceedings of the National Academy of Sciences USA 112: 7051-7054 doi

Ezenwa VO, Prieur-Richard AH, Roche B, Bailly X, Becquart P, García-Peña GE, Hosseini PR, Keesing F, Rizzoli A, Suzán G, Vignuzzi M, Vittecoq M, Mills JN, Guégan JF (2015) Interdisciplinarity and infectious diseases: an Ebola case study. PLoS Pathogens 11: e1004992 doi

Becquart P, Mahlakoiv T, Nkoghe D & Leroy EM (2014) Identification of continuous human B-cell epitopes in the VP35, VP40, nucleoprotein and glycoprotein of Ebola virus. PLoS One. 9: 96360 doi

Delicat-Loembet LM, Elguero E, Arnathau C, Durand P, Ollomo B, Ossari S, Mezui-Me-Ndong J, Mboro TM, Becquart P, Nkoghe D, Leroy E, Sica L, Gonzalez JP, Prugnolle F & Renaud F (2014) Prevalence of the sickle cell trait in Gabon: a nationwide study. Infection, Genetics and Evolution. 25: 52-56 doi

Yalcindag E, Rougeron V, Elguero E, Arnathau C, Durand P, Brisse S, Diancourt L, Aubouy A, Becquart P, D'Alessandro U, Fontenille D, Gamboa D, Maestre A, Menard D, Musset L, Noya O, Veron V, Wide A, Carme B, Legrand E, Chevillon C, Ayala FJ, Renaud F & Prugnolle F (2014) Patterns of selection on Plasmodium falciparum erythrocyte-binding antigens after the colonization of the New World. Molecular Ecology. 23: 1979-1993 doi

Prugnolle F, Rougeron V, Becquart P, Berry A, Makanga B, Rahola N, Arnathau C, Ngoubangoye B, Menard S, Willaume E, Ayala FJ, Fontenille D, Ollomo B, Durand P, Paupy C & Renaud F (2013) Diversity, host switching and evolution of Plasmodium vivax infecting African great apes. Proceedings of the National Academy of Sciences USA. 110: 8123-8128 doi

Caron M, Paupy C, Grard G, Becquart P, Mombo I, Nso BBB, Kassa FK, Nkoghe D & Leroy EM (2012) Recent introduction and rapid dissemination of chikungunya virus and dengue virus serotype 2 associated with human and mosquito coinfections in Gabon, Central Africa. Clinical Infectious Diseases. 55: e45-e53 doi

Fao P, Ky-Zerbo O, Gouem C, Somda P, Hien H, Ouedraogo PE, Kania D, Sanou A, Kossiwavi IA, Sanogo B, Ouedraogo M, Siribie I, Valea D, Ouedraogo S, Some R, Rouet F, Rollins N, McFetridge L, Naidu K, Luchters S, Reyners M, Irungu E, Katingima C, Mwaura M, Ouattara G, Mandaliya K, Wambua S, Thiongo M, Nduati R, Kose J, Njagi E, Mwaura P, Newell M-L, Mepham S, Viljoen J, Bland R, Mthethwa L, Bazin B, Rekacewicz C, Taylor A, Flowers N, Thigpen M, Fowler MG, Jamieson D, Mofenson LM, Read JS, Bork K, Cames C, Cournil A, Claeys P, Temmerman M, Van de Perre P, Becquart P, Foulongne V, Segondy M, de Vincenzi I, Gaillard P, Farley T, Habib N, Landoulsi S & Kesho Bora Study G (2012) Maternal HIV-1 disease progression 18-24 months postdelivery according to antiretroviral prophylaxis regimen (triple-antiretroviral prophylaxis during pregnancy and breastfeeding vs Zidovudine/single-dose nevirapine Prophylaxis): The Kesho Bora Randomized Controlled Trial. Clinical Infectious Diseases. 55: 449-460 doi

Nkoghe D, Kassa RF, Caron M, Grard G, Mombo I, Bikie B, Paupy C, Becquart P, Bisvigou U & Leroy EM (2012) Clinical forms of Chikungunya in Gabon, 2010. PLoS Neglected Tropical Diseases. 6: e1517 doi

Carthagena L, Becquart P, Hocini H, Kazatchkine MD, Bouhlal H & Belec L (2011) Modulation of HIV binding to epithelial cells and HIV transfer from immature dendritic cells to CD4 T lymphocytes by human lactoferrin and its major exposed LF-33 peptide. Open Virology Journal. 5: 27-34 doi

Leroy EM, Becquart P, Wauquier N & Baize S (2011) Evidence for Ebola virus superantigen activity. Journal of Virology. 85: 4041-4042 doi

Nkoghe D, Padilla C, Becquart P, Wauquier N, Moussavou G, Akue JP, Ollomo B, Pourrut X, Souris M, Kazanji M, Gonzalez JP & Leroy E (2011) Risk factors for Zaire ebolavirus-specific IgG in rural Gabonese populations. Journal of Infectious Diseases. 204: S768-S775 doi

Petitdemange C, Becquart P, Wauquier N, Beziat V, Debre P, Leroy EM & Vieillard V (2011) Unconventional repertoire profile is imprinted during acute Chikungunya infection for natural killer cells polarization toward cytotoxicity. PLoS Pathogens. 7: e1002268 doi

Wauquier N, Becquart P, Nkoghe D, Padilla C, Ndjoyi-Mbiguino A & Leroy EM (2011) The acute phase of Chikungunya virus infection in humans is associated with strong innate immunity and T CD8 cell activation. Journal of Infectious Diseases. 204: 115-123 doi

Becquart P, Wauquier N, Mahlakoiv T, Nkoghe D, Padilla C, Souris M, Ollomo B, Gonzalez JP, De Lamballerie X, Kazanji M & Leroy EM (2010) High prevalence of both humoral and cellular immunity to Zaire ebolavirus among rural populations in Gabon. PLoS One. 5: e9126

Becquart P, Wauquier N, Nkoghe D, Ndjoyi-Mbiguino A, Padilla C, Souris M & Leroy EM (2010) Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production. BMC Infectious Diseases. 10: 356

Rouet F, Foulongne V, Viljoen J, Steegen K, Becquart P, Valea D, Danaviah S, Segondy M, Verhofstede C & Van de Perre P (2010) Comparison of the Generic HIV Viral Load assay with the Amplicor HIV-1 monitor v1.5 and Nuclisens HIV-1 EasyQ v1.2 techniques for plasma HIV-1 RNA quantitation of non-B subtypes: the Kesho Bora preparatory study. Journal of Virological Methods. 163: 253-257 doi

Wauquier N, Becquart P, Padilla C, Baize S & Leroy EM (2010) Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis. PLoS Neglected Tropical Diseases. 4: e837 doi

Wauquier N, Padilla C, Becquart P, Leroy E & Vieillard V (2010) Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection. Immunogenetics. 62: 767-771

Leroy EM, Nkoghe D, Ollomo B, Nze-Nkogue C, Becquart P, Grard G, Pourrut X, Charrel R, Moureau G, Ndjoyi-Mbiguino A & de Lamballerie X (2009) Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007. Emerging Infectious Diseases. 15: 591-593

Tuaillon E, Valea D, Becquart P, Al Tabaa Y, Meda N, Bollore K, Van de Perre P & Vendrell JP (2009) Human milk-derived B cells: a highly activated switched memory cell population primed to secrete antibodies. Journal of Immunology. 182: 7155-7162

Wauquier N, Becquart P, Gasquet C & Leroy EM (2009) Immunoglobulin G in Ebola outbreak survivors, Gabon. Emerging Infectious Diseases. 15: 1136-1137

Chomont N, Hocini H, Gody JC, Bouhlal H, Becquart P, Krief-Bouillet C, Kazatchkine M & Belec L (2008) Neutralizing monoclonal antibodies to human immunodeficiency virus type 1 do not inhibit viral transcytosis through mucosal epithelial cells. Virology. 370: 246-254

Nagot N, Ouedraogo A, Konate I, Weiss HA, Foulongne V, Defer MC, Sanon A, Becquart P, Segondy M, Sawadogo A, Van de Perre P & Mayaud P (2008) Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels. Journal of Infectious Diseases. 198: 241-249

Nagot N, Ouedraogo A, Weiss HA, Konate I, Sanon A, Defer MC, Sawadogo A, Andonaba JB, Vallo R, Becquart P, Segondy M, Mayaud P & Van de Perre P (2008) Longitudinal effect following initiation of highly active antiretroviral therapy on plasma and cervico-vaginal HIV-1 RNA among women in Burkina Faso. Sexually Transmitted Infections. 84: 167-170 doi

Becquart P, Courgnaud V, Willumsen J & Van de Perre P (2007) Diversity of HIV-1 RNA and DNA in breast milk from HIV-1-infected mothers. Virology. 363: 256-260

Chomont N, Hocini H, Gresenguet G, Brochier C, Bouhlal H, Andreoletti L, Becquart P, Charpentier C, de Dieu Longo J, Si-Mohamed A, Kazatchkine MD & Belec L (2007) Early archives of genetically-restricted proviral DNA in the female genital tract after heterosexual transmission of HIV-1. AIDS. 21: 153-162 doi

Courgnaud V, Seng R, Becquart P, Boulahtouf A, Rouzioux C, Boufassa F, Deveau C, Van De Perre P, Meyer L & Foulongne V (2007) HIV-1 co-infection prevalence in two cohorts of early HIV-1 seroconverters in France. Aids. 21: 1055-1056

Nagot N, Ouedraogo A, Foulongne V, Konate I, Weiss HA, Vergne L, Defer MC, Djagbare D, Sanon A, Andonaba JB, Becquart P, Segondy M, Vallo R, Sawadogo A, Van de Perre P & Mayaud P (2007) Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. New England Journal of Medicine. 356: 790-799

Petitjean G, Becquart P, Tuaillon E, Al Tabaa Y, Valea D, Huguet MF, Meda N, Van de Perre P & Vendrell JP (2007) Isolation and characterization of HIV-1-infected resting CD4+ T lymphocytes in breast milk. Journal of Clinical Virology. 39: 1-8

Becquart P, Foulongne V, Willumsen J, Rouzioux C, Segondy M & Van de Perre P (2006) Quantitation of HIV-1 RNA in breast milk by real time PCR. Journal of Virological Methods. 133: 109-111 doi

Becquart P, Petitjean G, Tabaa YA, Valea D, Huguet MF, Tuaillon E, Meda N, Vendrell JP & Van de Perre P (2006) Detection of a large T-cell reservoir able to replicate HIV-1 actively in breast milk. AIDS. 20: 1453-1455 doi

Petitjean G, Becquart P, Al Tabaa Y, Vendrell JP & Van de Perre P (2006) Compartment-specific HIV-1 resting T-cell reservoirs. Aids. 20: 1338-1340 doi

Nagot N, Foulongne V, Becquart P, Mayaud P, Konate I, Ouedraogo A, Defer MC, Weiss H, Van de Perre P & Segondy M (2005) Longitudinal assessment of HIV-1 and HSV-2 shedding in the genital tract of West African women. Journal of Acquired Immune Deficiency Syndromes. 39: 632-634

Fondere JM, Petitjean G, Huguet MF, Salhi SL, Baillat V, Macura-Biegun A, Becquart P, Reynes J & Vendrell JP (2004) Human immunodeficiency virus type 1 (HIV-1) antigen secretion by latently infected resting CD4+ T lymphocytes from HIV-1-infected individuals. Journal of Virology. 78: 10536-10542 [- correction: doi -]

Belec L, Legoff J, Si-Mohamed A, Bloch F, Mbopi Keou FX, Becquart P, Matta M, Prazuck T & Petite JP (2003) Mucosal humoral immune response to hepatitis C virus E1/E2 surface glycoproteins and HCV shedding in saliva and cervicovaginal fluids from chronically HCV-infected patients. Journal of Hepatology. 38: 833-842

Becquart P, Chomont N, Roques P, Ayouba A, Kazatchkine MD, Belec L & Hocini H (2002) Compartmentalization of HIV-1 between breast milk and blood of HIV-infected mothers. Virology. 300: 109-117

Belec L, Ghys PD, Hocini H, Nkengasong JN, Tranchot-Diallo J, Diallo MO, Ettiegne-Traore V, Maurice C, Becquart P, Matta M, Si-Mohamed A, Chomont N, Coulibaly IM, Wiktor SZ & Kazatchkine MD (2001) Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women. Journal of Infectious Diseases. 184: 1412-1422

Chomont N, Gresenguet G, Hocini H, Becquart P, Matta M, Andreoletti L, Si-Mohamed A, Carreno MP, Kazatchkine M & Belec L (2001) Polymerase chain reaction for Y chromosome to detect semen in cervicovaginal fluid: a prerequisite to assess HIV-specific vaginal immunity and HIV genital shedding. Aids. 15: 801-802

Chomont N, Gresenguet G, Levy M, Hocini H, Becquart P, Matta M, Tranchot-Diallo J, Andreoletti L, Carreno MP, Kazatchkine MD & Belec L (2001) Detection of Y chromosome DNA as evidence of semen in cervicovaginal secretions of sexually active women. Clinical and Diagnostic Laboratory Immunology. 8: 955-958

Hocini H, Becquart P, Bouhlal H, Chomont N, Ancuta P, Kazatchkine MD & Belec L (2001) Active and selective transcytosis of cell-free human immunodeficiency virus through a tight polarized monolayer of human endometrial cells. Journal of Virology. 75: 5370-5374

Becquart P, Hocini H, Levy M, Sepou A, Kazatchkine MD & Belec L (2000) Secretory anti-human immunodeficiency virus (HIV) antibodies in colostrum and breast milk are not a major determinant of the protection of early postnatal transmission of HIV. Journal of Infectious Diseases. 181: 532-539

Ghys PD, Belec L, Diallo MO, Ettiegne-Traore V, Becquart P, Maurice C, Nkengasong JN, Coulibaly IM, Greenberg AE, Laga M & Wiktor SZ (2000) Cervicovaginal anti-HIV antibodies in HIV-seronegative female sex workers in Abidjan, Cote d'Ivoire. Aids. 14: 2603-2608

Hocini H, Becquart P, Bouhlal H, Adle-Biassette H, Kazatchkine MD & Belec L (2000) Secretory leukocyte protease inhibitor inhibits infection of monocytes and lymphocytes with human immunodeficiency virus type 1 but does not interfere with transcytosis of cell-associated virus across tight epithelial barriers. Clinical and Diagnostic Laboratory Immunology. 7: 515-518

Becquart P, Gresenguet G, Hocini H, Kazatchkine MD & Belec L (1999) Secretory leukocyte protease inhibitor in colostrum and breast milk is not a major determinant of the protection of early postnatal transmission of HIV. Aids. 13: 2599-2602

Becquart P, Hocini H, Garin B, Sepou A, Kazatchkine MD & Belec L (1999) Compartmentalization of the IgG immune response to HIV-1 in breast milk. Aids. 13: 1323-1331

Becquart P, Garin B, Sepou A, Hocini H, Brogan T, Menu E, Barre-Sinoussi F, Kazatchkine M & Belec L (1998) High incidence of early postnatal transmission of human immunodeficiency virus type 1 in Bangui, Central African Republic. Journal of Infectious Diseases. 177: 1770-1771

Belec L, Dupre T, Tevi-Benissan C, Prazuck T, Becquart P, Hocini H & Gilquin J (1997) Cervicovaginal HIV-1 and HIV-2 cross-reactivities. International Journal of STD & AIDS. 8: 68

Hocini H, Belec L, Iscaki S, Garin B, Pillot J, Becquart P & Bomsel M (1997) High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160. AIDS Research and Human Retroviruses. 13: 1179-1185

Mohamed AS, Becquart P, Hocini H, Metais P, Kazatchkine M & Belec L (1997) Dilution assessment of cervicovaginal secretions collected by vaginal washing to evaluate mucosal shedding of free human immunodeficiency virus. Clinical and Diagnostic Laboratory Immunology. 4: 624-626