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Surname : VERGNES
Name : Baptiste
Team : GeneSys
Grade : IR
Email address : This email address is being protected from spambots. You need JavaScript enabled to view it.
Fax : (+33) 4 67 41 62 99
Locality : IRD Montpellier
Employer : IRD

Publications :

Gazanion E, Vergnes B (2018) Protozoan parasite auxotrophies and metabolic dependencies. Experientia supplementum 109: 351-375 doi

Mesquita I, Vergnes B, Silvestre R (2018) Alterations on cellular redox states upon infection and implications for host cell homeostasis. Experientia supplementum 109: 197-220 doi

Alten B, Maia C, Afonso MO, Campino L, Jimenez M, Gonzalez E, Molina R, Bañuls AL, Prudhomme J, Vergnes B, Toty C, Cassan C, Rahola N, Thierry M, Sereno D, Bongiorno G, Bianchi R, Khoury C, Tsirigotakis N, Dokianakis E, Antoniou M, Christodoulou V, Mazeris A, Karakus M, Ozbel Y, Arserim SK, Kasap OE, Gunay F, Oguz G, Kaynas S, Tsertsvadze N, Tskhvaradze L, Giorgobiani E, Gramiccia M, Volf P, Gradoni L (2016) Seasonal dynamics of phlebotomine sand fly species proven vectors of Mediterranean leishmaniasis caused by Leishmania infantum. PLoS Neglected Tropical Diseases 10: e0004458 doi

Mesquita I, Varela P, Belinha A, Gaifem J, Laforge M, Vergnes B, Estaquier J, Silvestre R (2016) Exploring NAD(+) metabolism in host-pathogen interactions. Cellular and Molecular Life Sciences 73: 1225-1236 doi

Prudhomme J, Cassan C, Hide M, Toty C, Rahola N, Vergnes B, Dujardin JP, Alten B, Sereno D, Bañuls AL (2016) Ecology and morphological variations in wings of Phlebotomus ariasi (Diptera: Psychodidae) in the region of Roquedur (Gard, France): a geometric morphometrics approach. Parasites & Vectors 9: 578 doi

Vergnes B, Gazanion E, Grentzinger T (2016) Functional divergence of SIR2 orthologs between trypanosomatid parasites. Molecular and Biochemical Parasitology 207: 96-101 doi

Prudhomme J, Rahola N, Toty C, Cassan C, Roiz D, Vergnes B, Thierry M, Rioux JA, Alten B, Sereno D, Bañuls AL (2015) Ecology and spatiotemporal dynamics of sandflies in the Mediterranean Languedoc region (Roquedur area, Gard, France). Parasites & Vectors 8: 642 doi

Prudhomme J, Toty C, Kasap OE, Rahola N, Vergnes B, Maia C, Campino L, Antoniou M, Jimenez M, Molina R, Cannet A, Alten B, Sereno D, Bañuls AL (2015) New microsatellite markers for multi-scale genetic studies on Phlebotomus ariasi Tonnoir, vector of Leishmania infantum in the Mediterranean area. Acta Tropica. 142: 79-85 doi

Yazdanparast E, Dos Anjos A, Garcia D, Loeuillet C, Shahbazkia HR & Vergnes B (2014) INsPECT, an open-source and versatile software for automated quantification of (Leishmania) Intracellular Parasites. PLoS Neglected Tropical Diseases. 8: e2850 doi

Gazanion E, Seblova V, Votypka J, Vergnes B, Garcia D, Volf P & Sereno D (2012) Leishmania infantum nicotinamidase is required for late-stage development in its natural sand fly vector, Phlebotomus perniciosus. International Journal for Parasitology. 42: 323-327 doi

Ait-Oudhia K, Gazanion E, Oury B, Vergnes B & Sereno D (2011) The fitness of antimony-resistant Leishmania parasites: lessons from the field. Trends in Parasitology. 27: 141-142 doi

Ait-Oudhia K, Gazanion E, Vergnes B, Oury B & Sereno D (2011) Leishmania antimony resistance: what we know what we can learn from the field. Parasitology Research. 109: 1225-1232 doi

Gazanion E, Garcia D, Silvestre R, Gerard C, Guichou JF, Labesse G, Seveno M, Cordeiro-Da-Silva A, Ouaissi A, Sereno D & Vergnes B (2011) The Leishmania nicotinamidase is essential for NAD(+) production and parasite proliferation. Molecular Microbiology. 82: 21-38 doi

Gazanion E, Vergnes B, Seveno M, Garcia D, Oury B, Ait-Oudhia K, Ouaissi A & Sereno D (2011) In vitro activity of nicotinamide/antileishmanial drug combinations. Parasitology International. 60: 19-24 doi

Tavares J, Ouaissi A, Santarem N, Sereno D, Vergnes B, Sampaio P & Cordeiro-da-Silva A (2008) The Leishmania infantum cytosolic SIR2-related protein 1 (LiSIR2RP1) is an NAD+ -dependent deacetylase and ADP-ribosyltransferase. Biochemical Journal. 415: 377-386

Adriano MA, Vergnes B, Poncet J, Mathieu-Daudé F, da Silva AC, Ouaissi A & Sereno D (2007) Proof of interaction between Leishmania SIR2RP1 deacetylase and chaperone HSP83. Parasitology Research. 100: 811-818

Silvestre R, Cordeiro da Silva A, Santarem N, Vergnes B, Sereno D & Ouaissi A (2007) SIR2-deficient Leishmania infantum induces a defined IFN-gamma/IL-10 pattern that correlates with protection. Journal of Immunology. 179: 3161-3170

Vergnes B, Gourbal B, Girard I, Sundar S, Drummelsmith J & Ouellette M (2007) A proteomics screen implicates HSP83 and a small kinetoplastid calpain-related protein in drug resistance in Leishmania donovani clinical field isolates by modulating drug-induced programmed cell death. Molecular & Cellular Proteomics. 6: 88-101

Sereno D, Vergnes B, Mathieu-Daudé F, Cordeiro da Silva A & Ouaissi A (2006) Looking for putative functions of the Leishmania cytosolic SIR2 deacetylase. Parasitology Research. 100: 1-9

Borges M, Cordeiro-da-Silva A, Vergnes B, Sereno D & Ouaissi A (2005) Conversion of Trypanosoma cruzi Tc52 released factor to a protein inducing apoptosis. Tissue Cell. 37: 469-478

Sereno D, Alegre AM, Silvestre R, Vergnes B & Ouaissi A (2005) In vitro antileishmanial activity of nicotinamide. Antimicrobial Agents and Chemotherapy. 49: 808-812

Sereno D, Vanhille L, Vergnes B, Monte-Allegre A & Ouaissi A (2005) Experimental study of the function of the excreted/secreted Leishmania LmSIR2 protein by heterologous expression in eukaryotic cell line. Kinetoplastid Biology and Disease. 4: 1

Vergnes B, Sereno D, Tavares J, Cordeiro-da-Silva A, Vanhille L, Madjidian-Sereno N, Depoix D, Monte-Alegre A & Ouaissi A (2005) Targeted disruption of cytosolic SIR2 deacetylase discloses its essential role in Leishmania survival and proliferation. Gene. 363: 85-96

Vergnes B, Vanhille L, Ouaissi A & Sereno D (2005) Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase. Acta Tropica. 94: 107-115

Cordeiro-da-Silva A, Cardoso L, Araujo N, Castro H, Tomas A, Rodrigues M, Cabral M, Vergnes B, Sereno D & Ouaissi A (2003) Identification of antibodies to Leishmania silent information regulatory 2 (SIR2) protein homologue during canine natural infections: pathological implications. Immunology Letters. 86: 155-162

Vergnes B, Sereno D, Madjidian-Sereno N, Lemesre JL & Ouaissi A (2002) Cytoplasmic SIR2 homologue overexpression promotes survival of Leishmania parasites by preventing programmed cell death. Gene. 296: 139-150