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Biodiversity of infectious systems: from Gene to Ecosystem

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Context :

 While knowledge and caracterisation of the actors of infectious systems (hosts / parasites / vectors / environment) improve, mechanisms of emergence or re-remergence of infectious diseases still remain poorly known. The increase in the number of cases of resistance to drugs, and the emergence of multi-resistant strains, are indicative of constantly evolving infectious systems. These considerations are especially fundamental as the extent of exchanges linked to globalisation intensely upset the equilibrium of ecosystems, and nobody can assume the consequences of this globalisation on the evolution of infectious diseases.


Objectives :

Our projects use speficic and complementary skills for an integrative research, in order to describe, understand and predict the dynamic of infectious diseases, and to help to set up or adapt efficient methods of control.

Our study models are leishmaniases and their vectors, th sandflies; and the bacterian models Mycobacterium tuberculosis and Staphylococcus aureus, which are major problems of public health, especially in the South. Other infectious diseases such as cholera, whooping cough or  meningitis are studied to answer specific problematics.

Collaborations with the South are at the heart of our reseach projects, especially through the strong links established in South-east (Vietnam, Laos, Cambodia), Senegal, Burkina Faso and North Africa.


Our project can be divided in five axis: