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Nom : LOPEZ-RUBIO
Prénom : José-Juan
Equipe : BioGEPPE
Grade : CR1
Adresse email : Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.
Téléphone : (+33) 4 67 54 95 28
Fax : (+33) 4 67 41 62 99
Implantation : CHU La Colombière
Appartenance : INSERM

Publications :

Dorin-Semblat D, Tetard M, Claes A, Semblat JP, Dechavanne S, Fourati Z, Hamelin R, Armand F, Matesic G, Nunes-Silva S, Srivastava A, Gangnard S, Lopez-Rubio JJ, Moniatte M, Doerig C, Scherf A, Gamain B (2019) Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA. PLoS Biology 17: e3000308 doi

Belmonte-Reche E, Martinez-Garcia M, Guedin A, Zuffo M, Arevalo-Ruiz M, Doria F, Campos-Salinas J, Maynadier M, Lopez-Rubio JJ, Freccero M, Mergny JL, Perez-Victoria JM, Morales JC (2018) G-quadruplex identification in the genome of protozoan parasites points to naphthalene diimide ligands as new antiparasitic agents. Journal of Medicinal Chemistry 61: 1231-1240 doi

Neveu G, Dupuy F, Ladli M, Barbieri D, Naissant B, Richard C, Martins RM, Lopez-Rubio JJ, Bachmann A, Verdier F, Lavazec C (2018) Plasmodium falciparum gametocyte-infected erythrocytes do not adhere to human primary erythroblasts. Scientific Reports 8: 17886 doi

Chan S, Frasch A, Mandava CS, Ch'ng JH, Quintana MD, Vesterlund M, Ghorbal M, Joannin N, Franzen O, Lopez-Rubio JJ, Barbieri S, Lanzavecchia A, Sanyal S, Wahlgren M (2017) Regulation of pfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor. Nature Microbiology 2: 17068 doi

Bandje K, Naissant B, Bigey P, Lohezic M, Vayssieres M, Blaud M, Kermasson L, Lopez-Rubio JJ, Langsley G, Lavazec C, Deloron P, Merckx (2016) Characterization of an A-kinase anchoring protein-like suggests an alternative way of PKA anchoring in Plasmodium falciparum. Malaria Journal 15: 248 doi

Mbengue A, Bhattacharjee S, Pandharkar T, Liu H, N, Estiu G, Stahelin RV, Rizk S, S, Njimoh D, L, Ryan Y, Chotivanich K, Nguon C, Ghorbal M, Lopez-Rubio JJ, Pfrender M, Emrich S, Mohandas N, Dondorp AM, Wiest O, Haldar K (2015) A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature. 520: 683-687 doi

Sollelis L, Ghorbal M, MacPherson CR, Martins RM, Kuk N, Crobu L, Bastien P, Scherf A, Lopez-Rubio JJ, Sterkers Y (2015) First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites. Cellular Microbiology 17: 1405-1412 doi

Ghorbal M, Gorman M, Macpherson CR, Martins RM, Scherf A & Lopez-Rubio JJ (2014) Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system. Nature Biotechnology. 32: 819-821 doi pdf

Ghorbal M, Scheidig-Benatar C, Bouizem S, Thomas C, Paisley G, Faltermeier C, Liu M, Scherf A, Lopez-Rubio JJ & Gopaul DN (2012) Initial characterization of the Pf-Int recombinase from the malaria parasite Plasmodium falciparum. PLoS One. 7: e46507 doi