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Nom : CROBU
Prénom : Lucien
Equipe : BioGEPPE
Grade : AI
Adresse email : Cette adresse e-mail est protégée contre les robots spammeurs. Vous devez activer le JavaScript pour la visualiser.
Téléphone : (+33) 4 67 63 55 13
Implantation : CHU La Colombière
Appartenance : CNRS

Publications :

Garcia-Silva MR, Sollelis L, MacPherson CR, Stanojcic S, Kuk N, Crobu L, Bringaud F, Bastien P, Page M, Scherf A, Sterkers Y (2017) Identification of the centromeres of Leishmania major: revealing the hidden pieces. EMBO Reports 18: 1968-1977 doi

Stanojcic S, Sollelis L, Kuk N, Crobu L, Balard Y, Schwob E, Bastien P, Pagès M, Sterkers Y (2016) Single-molecule analysis of DNA replication reveals novel features in the divergent eukaryotes Leishmania and Trypanosoma brucei versus mammalian cells. Scientific Reports 6: 23142 doi

Tetaud E, Lefebvre M, M'Bang-Benet DE, Crobu L, Blancard C, Sterkers Y, Pagès M, Bastien P, Merlin G (2016) TbFlabarin, a flagellar protein of Trypanosoma brucei, highlights differences between Leishmania and Trypanosoma flagellar-targeting signals. Experimental Parasitology 166: 97-107 doi

Mbang-Benet DE, Sterkers Y, Crobu L, Sarrazin A, Bastien P, Pagès M (2015) RNA interference screen reveals a high proportion of mitochondrial proteins essential for correct cell cycle progress in Trypanosoma brucei. BMC Genomics 16: 297 doi

Morelle C, Sterkers Y, Crobu L, Mbang-Benet DE, Kuk N, Portales P, Bastien P, Pagès M, Lachaud L (2015) The nucleoporin Mlp2 is involved in chromosomal distribution during mitosis in trypanosomatids. Nucleic Acids Research 43: 4013-4027 doi

Sollelis L, Ghorbal M, MacPherson CR, Martins RM, Kuk N, Crobu L, Bastien P, Scherf A, Lopez-Rubio JJ, Sterkers Y (2015) First efficient CRISPR-Cas9-mediated genome editing in Leishmania parasites. Cellular Microbiology 17: 1405-1412 doi

Lachaud L, Bourgeois N, Kuk N, Morelle C, Crobu L, Merlin G, Bastien P, Pagès M & Sterkers Y (2014) Constitutive mosaic aneuploidy is a unique genetic feature widespread in the Leishmania genus. Microbes and Infection. 16: 61-66 doi

Mbang-Benet DE, Sterkers Y, Morelle C, Kebe NM, Crobu L, Portales P, Coux O, Hernandez JF, Meghamla S, Pagès M & Bastien P (2014) The bacterial-like HslVU protease complex subunits are involved in the control of different cell cycle events in trypanosomatids. Acta Tropica. 131: 22-31 doi

Sterkers Y, Crobu L, Lachaud L, Pagès M & Bastien P (2014) Parasexuality and mosaic aneuploidy in Leishmania: alternative genetics. Trends in Parasitology. 30: 429-435 doi

Sterkers Y, Lachaud L, Bourgeois N, Crobu L, Bastien P & Pagès M (2012) Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania. Molecular Microbiology. 86: 15-23 doi

Sterkers Y, Lachaud L, Crobu L, Bastien P & Pagès M (2011) FISH analysis reveals aneuploidy and continual generation of chromosomal mosaicism in Leishmania major. Cellular Microbiology. 13: 274-283 doi

Casanova M, Crobu L, Blaineau C, Bourgeois N, Bastien P & Pagès M (2009) Microtubule-severing proteins are involved in flagellar length control and mitosis in Trypanosomatids. Molecular Microbiology. 71: 1353-1370

Casanova M, Portales P, Blaineau C, Crobu L, Bastien P & Pagès M (2008) Inhibition of active nuclear transport is an intrinsic trigger of programmed cell death in trypanosomatids. Cell Death and Differentiation. 15: 1910-1920

Blaineau C, Tessier M, Dubessay P, Tasse L, Crobu L, Pagès M & Bastien P (2007) A novel microtubule-depolymerising kinesin involved in length control of a eukaryotic flagellum. Current Biology. 17: 778-782

Chargui N, Bastien P, Kallel K, Haouas N, Akrout FM, Masmoudi A, Zili J, Chaker E, Ben Othman AD, Azaiez R, Crobu L, Mezhoud H & Babba H (2005) Usefulness of PCR in the diagnosis of cutaneous leishmaniasis in Tunisia. Transactions of the Royal Society of Tropical Medicine and Hygiene. 99: 762-768

Chabbert E, Lachaud L, Crobu L & Bastien P (2004) Comparison of two widely used PCR primer systems for detection of Toxoplasma in amniotic fluid, blood, and tissues. Journal of Clinical Microbiology. 42: 1719-1722